Lipid Profiles of Children With Down Syndrome Compared With Their Siblings

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Lipid profiles of children with Down syndrome compared with their siblings.

OBJECTIVES Our objective was to compare serum lipid profiles, total cholesterol (TC), low-density lipoprotein (LDL), triglycerides (TG), and high-density lipoprotein (HDL) between children with Down syndrome (DS) and their non-DS siblings. We hypothesized that the children with DS would have higher TC, LDL, and TG and lower HDL. The secondary aim was to explore if the difference in lipid profil...

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Erythrocyte phospholipid molecular species and fatty acids of Down syndrome children compared with non-affected siblings.

The majority of children with Down syndrome (DS) develop Alzheimer's disease (AD) at an early age. Although long-chain n-3 fatty acids (FA) are protective of neurodegeneration, little is known about the FA status in DS. In the present study, we aimed to investigate whether children with DS presented altered plasma and erythrocyte membrane phospholipids (PL) FA composition, when compared with th...

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Speech Intelligibility in Persian Children with Down Syndrome

Objectives: One of the most effective methods to describe speech disorders is the measurement of speech intelligibility. The speech intelligibility indicates the extent of acoustic signals that correctly speaker produces and hearer receives. The purpose of this study was to investigate the speech intelligibility in the Persian children with Down syndrome, age range was 3 to 5 years, who had spo...

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ژورنال

عنوان ژورنال: PEDIATRICS

سال: 2012

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2011-1262